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Light-activated 'CRISPR' enables fast, precise gene editing and detection of DNA repair（图）
Light-activated CRISPR enables fast precise gene editing detection DNA repair
2020/6/23
In a series of experiments co-funded by the National Science Foundation, scientists at Johns Hopkins have used light as a trigger to make quick, precise cuts in the genomic material of ...
2017 基因组不稳定性和DNA修复 Keystone Symposia（2017 Keystone Symposia on Genomic Instability and DNA Repair）
Genomic Instability DNA Repair
2017/3/7
The meeting will begin on Sunday, April 2 with registration from 16:00 to 20:00 and a welcome mixer from 18:00 to 20:00. Conference events conclude on Thursday, April 6 with a closing plenary session ...
2017哺乳动物DNA修复高登研究研讨会（The Gordon Research Seminar on Mammalian DNA Repair）
2017 哺乳动物DNA修复高登研究 研讨会
2017/2/13
The Gordon Research Seminar on Mammalian DNA Repair is a unique forum for graduate students, post-docs, and other scientists with comparable levels of experience and education to present and exchange ...
Metnase is a novel bifunctional protein that contains a SET domain and a transposase domain. Metnase contains sequence-specific DNA binding activity and sequence non-specific DNA cleavage activity, as...
ELUCIDATING THE ROLE OF REDOX EFFECTS AND THE KU80 C-TERMINAL REGION IN THE REGULATION OF THE HUMAN DNA REPAIR PROTEIN KU
DNA-PKcs regulation Ku NHEJ
2015/5/25
DNA double strand breaks (DSB) are among the most lethal forms of DNA damage and can occur as a result of ionizing radiation (IR), radiomimetic agents, endogenous DNA-damaging agents, etc. If left unr...
The influence of the Ku80 carboxy-terminus on activation of the DNA-dependent protein kinase and DNA repair is dependent on the structure of DNA cofactors
DNA-PK Ku70/80 Ku80 Carboxy Terminus
2015/5/25
In mammalian cells DNA double strand breaks (DSBs) are highly variable with respect to sequence and structure all of which are recognized by the DNA- dependent protein kinase (DNA-PK), a critical comp...
New lab technique simultaneously reveals structure and function of proteins critical in DNA repair
structure and function proteins critical DNA repair
2015/4/17
By combining two highly innovative experimental techniques, scientists at the University of Illinois at Urbana-Champaign have for the first time simultaneously observed the structure and the correlate...
The ability to accurately repair DNA damaged by spontaneous errors, oxidation or mutagens is crucial to the survival of cells. This repair is normally accomplished by using an identical or homologous ...
XPC DNA REPAIR PROTEIN REGULATION IN THE CONTEXT OF THE G1/S CELL CYCLE CHECKPOINT
XPC DNA repair retinoblastoma protein cell cycle
2010/5/21
DNA is subject to various types of damage that can impair cellular function or cause cell death. DNA damage blocks normal cellular processes such as replication and transcription and can have catastro...
北京师范大学分子生物学课件CHAPTER 6 Mutations, Mutagenesis and DNA Repair
北京师范大学 分子生物学 课件 Mutations Mutagenesis DNA Repair
2009/11/14
北京师范大学分子生物学课件CHAPTER 6 Mutations, Mutagenesis and DNA Repair。
线粒体DNA修复系统相关酶的研究进展 Progress of Enzyme in Mitochondrial DNA Repair System
线粒体DNA DNA修复 酶 研究进展
2008/1/10
摘要线粒体DNA（mtDNA）编码线粒体电子传递系统的亚单位以及构建翻译机器所需的各种rRAN和tRNA。mtDNA编码的每一个亚单位都是线粒体完成正常的氧化磷酸化过程所必需的，因此，线粒体DNA的完整性对于生物体的生存十分重要。长期以来，人们一直认为线粒体中不存在DNA的修复。近年来在线粒体提取物中却检测到了一定数量的修复因子，提示线粒体中存在DNA的修复。主要对线粒体修复系统中相关酶的研究进展...