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Seryl-tRNA Synthetases from Methanogenic Archaea: Suppression of Bacterial Amber Mutation and Heterologous Toxicity
seryl-tRNA synthetase heterologous toxicity amber suppression methanogenic archaea
2010/12/14
Methanogenic archaea possess unusual seryl-tRNA synthetases (SerRS), evolutionarily
distinct from the SerRSs found in other archaea, eucaryotes and bacteria. Our recent X-ray
structural analysis of ...
The in vivo Expression of Streptomyces rimosus tRNA Genes
Streptomyces rimosus expression promoter
2009/3/23
The expression of seven tRNA genes from Streptomyces rimosus, cloned on bifunctional plasmids, has been studied in a homologous (S. rimosus) and a heterologous (Escherichia coli) system. Analyzed gene...
Aminoacyl-tRNA Synthesis in Methanogenic Archaea
aminoacyl-tRNA methanogenic Archaea evolution tRNA translation
2009/3/20
Aminoacyl-tRNA synthetases (AARSs) are essential for faithful translation of the genetic code and have long been studied intensively. Major discoveries explained basic principles of how amino acids ar...
The Accuracy of Seryl-tRNA Synthesis
aminoacyl-tRNA synthetase tRNA-dependent amino acid recognition amino acid selection
2009/3/20
The high level of translational fidelity is ensured by various types of quality control mechanisms, which are adapted to prevent or correct naturally occurring mistakes. Accurate aminoacyl-tRNA synthe...