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Study finds a new way to shut down cancer cells’ ability to consume glucose（图）
shut down cancer cells ability to consume glucose
2017/11/7
Cancer cells consume exorbitant amounts of glucose, a key source of energy, and shutting down this glucose consumption has long been considered a logical therapeutic strategy. However, good pharmacolo...
The SLC2A14 gene, encoding the novel glucose/dehydroascorbate transporter GLUT14, is associated with inflammatory bowel disease
genetic association SLC2A14 vitamin C antioxidants inflammatory bowel disease
2017/9/27
Background: Variations in intestinal antioxidant membrane transporters are implicated in the initiation and progression of inflammatory bowel disease (IBD). Facilitated glucose transporter member 14 (...
Duodenal and ileal glucose infusions differentially alter gastrointestinal peptides, appetite response, and food intake: a tube feeding study
glucose appetite food intake brake ileum duodenum GLP-1 PYY ghrelin
2017/7/12
Background: Activation of the ileal brake through the delivery of nutrients into the distal small intestine to promote satiety and suppress food intake provides a new target for weight loss. Evidence ...
Injectable Solution May Provide Weeks of Glucose Control
Injectable Solution Glucose Control
2017/6/5
Biomedical engineers at Duke University have created a technology that might provide weeks of glucose control for diabetes with a single injection, which would be a dramatic improvement over current t...
Inhibition of sweet chemosensory receptors alters insulin responses during glucose ingestion in healthy adults: a randomized crossover interventional study
sweet taste receptors lactisole glucose intolerance insulin saccharin artificial sweeteners OGTT modeling analysis
2017/3/1
Background: Glucose is a natural ligand for sweet taste receptors (STRs) that are expressed on the tongue and in the gastrointestinal tract. Whether STRs directly contribute to the regulation of gluco...
Longitudinal association between fasting blood glucose concentrations and first stroke in hypertensive adults in China: effect of folic acid intervention
Chinese folic acid hyperglycemia hypertension stroke
2017/1/25
Background: Diabetes is a known risk factor for stroke, but data on its prospective association with first stroke are limited. Folic acid supplementation has been shown to protect against first stroke...
Reformulating cereal bars: high resistant starch reduces in vitro digestibility but not in vivo glucose or insulin response; whey protein reduces glucose but disproportionately increases insulin
randomized clinical trial blood glucose humans insulinemic response postprandial glycemic response
2016/8/31
Background: Resistant starch (RS) and whey protein are thought to be effective nutrients for reducing glycemic responses.
Reformulating cereal bars: high resistant starch reduces in vitro digestibility but not in vivo glucose or insulin response; whey protein reduces glucose but disproportionately increases insulin
randomized clinical trial blood glucose humans insulinemic response postprandial glycemic response
2016/8/31
Background: Resistant starch (RS) and whey protein are thought to be effective nutrients for reducing glycemic responses.
No differential effect of beverages sweetened with fructose, high-fructose corn syrup, or glucose on systemic or adipose tissue inflammation in normal-weight to obese adults: a randomized controlled trial
sugar-sweetened beverages systemic inflammation adipose tissue inflammation fructose intestinal permeability
2016/6/29
Background: Sugar-sweetened beverage (SSB) consumption and low-grade chronic inflammation are both independently associated with type 2 diabetes and cardiovascular disease. Fructose, a major component...
No differential effect of beverages sweetened with fructose, high-fructose corn syrup, or glucose on systemic or adipose tissue inflammation in normal-weight to obese adults: a randomized controlled trial
sugar-sweetened beverages systemic inflammation adipose tissue inflammation fructose intestinal permeability
2016/6/29
Background: Sugar-sweetened beverage (SSB) consumption and low-grade chronic inflammation are both independently associated with type 2 diabetes and cardiovascular disease. Fructose, a major component...
De novo lipogenesis during controlled overfeeding with sucrose or glucose in lean and obese women
De novo lipogenesis deuterium overfeeding
2016/6/14
The results of previous studies suggest that de novo
lipogenesis may play an important role in the etiology of obesity,
particularly during overconsumption of different carbohydrates.
Simple skinfold-thickness measurements complement conventional anthropometric assessments in predicting glucose tolerance
anthropometry body composition skinfold thickness
2016/6/12
Skinfold-thickness measurements are considered
to have limited clinical utility.
Whole-body and adipose tissue glucose metabolism in response to short-term fasting in lean and obese women
Abdominal obesity glucose uptake leptin
2016/6/12
Alterations in glucose metabolism during early
fasting may be an important trigger of the hormonal and metabolic
responses to fasting.
Serum chromium does not predict glucose tolerance in late pregnancy
pregnancy triacylglycerol cholesterol
2016/6/12
Chromium is an essential element in human nutrition.
Serum concentrations of chromium are not well characterized
during pregnancy or in gestational diabetes mellitus.
Dietary fish as a major component of a weight-loss diet: effect on serum lipids, glucose, and insulin metabolism in overweight hypertensive subjects
insulin hypertension humans
2016/6/1
Obesity in hypertensive patients is associated with
dyslipidemia and insulin resistance, both of which are improved
by weight control. n23 Fatty acids have diverse effects on mechanisms
underlying ...