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Hypoxia Inducible Factor-1α (HIF-1 α) and its Role in Tumour Progression to Malignancy
HIF HIF-1α Hypoxia Malignancy Cancer Cancer Therapy
2015/7/28
Hypoxia is a condition in which an area of the body or a tissue is deprived of sufficient supply of oxygen. The lack of nutrients in a hypoxic tissue generally causes apoptosis but some cells are able...
Stress-inducible Mig6 promotes pancreatic beta cell destruction in the pathogenesis of diabetes
Diabetes Pancreatic beta cells EGFR Mig6
2015/5/22
Pancreatic insulin-secreting beta cell failure is central to the development of diabetes. Therapeutic applications targeted at understanding and manipulating beta cell destruction mechanisms should en...
Tsg-6 : an inducible mediator of paracrine anti-inflammatory and myeloprotective effects of adipose stem cells
Adipose stem cell inflammation TSG-6 hematopoiesis smoking
2015/5/22
Tumor necrosis factor-induced protein 6 (TSG-6) has been shown to mitigate inflammation. Its presence in the secretome of adipose stem / stromal cells (ASC) and its role in activities of ASC have been...
Expression and Function of the Inducible Costimulator Ligand B7-H2 in Human Airway Smooth Muscle Cells
airway inflammation airway smooth muscle cells B7-H2 DNA synthesis inducible costimulator
2009/12/15
The data demonstrate that ASM cells express functionally active B7-H2, CD40 and OX40L and suggest that B7-H2-dependent signaling may play an active role in a proliferative response rather than in cyto...
D-Test Method for Detection of Inducible Clindamycin Resistance in Staphylococcus aureus
Methicilin resistance Staphylococcus aureus Clindamycin D-test Disk diffusion
2009/11/26
Objective:Methicillin resistant staphylococcus aureus (MRSA) is a frequent cause of infections in children. The purpose of this study was to determine the frequency of nasal colonization of S. aureus ...
The importance of inducible clindamycin resistance in enterotoxin positive S. aureus isolated from clinical samples
Clindamycin inducible resistance S.aureus enterotoxin A
2009/11/24
The importance of inducible clindamycin resistance in enterotoxin positive S. aureus isolated from clinical samples。
Antimicrobial susceptibility,inducible macrolide-lincosamide-streptogramin B,and clonal diversity patterns of nosocomial methicillin-resistant Staphylococcus aureus strains isolated in Hacettepe University adult hospital
Methicillin-resistant Staphylococcus aureus (MRSA) antibiotic susceptibility inducible macrolide-lincosamide-streptogramin B (iMLSB) pulse field gel electrophoresis (PFGE)
2009/6/23
Aim: Nosocomial infections due to methicillin resistant Staphylococcus aureus (MRSA) are an important problem with limited therapeutic options. The aim of this study was to determine the vancomycin, t...
Reversal of Endotoxin-Induced Hypotension by Inhibition of Inducible Nitric Oxide Synthase Activity is Associated with Improved Oxidative Status in Rat Heart,Aorta and Mesenteric Artery
Rat endotoxin hypotension inducible nitric oxide synthase lipid peroxidation
2009/6/19
Overproduction of reactive oxygen and nitrogen species leads to oxidative stress and decreased total antioxidant capacity, which is responsible for high mortality from several diseases such as endotox...
Vanadate-induced expression of hypoxia inducible factor-1α via oxygen-dependent and -independent pathways
HIF-1α vanadium cobalt 17-AAG
2009/4/1
Increase in hypoxia-inducible factor-1α (HIF-1α) expression is caused by some essential trace elements such as vanadium and cobalt even under normoxic conditions. The mechanism of HIF-1α activation ca...
Expression of inducible nitric oxide synthase in smooth muscle cells from rat penile corpora cavernosa
inducible nitric oxide synthase smooth muscle cells rat penile corpora cavernosa
2009/2/13
Nitric oxide (NO), the main mediator of penile erection, is assumed to be synthesized in the penis by the neuronal constitutive nitric oxide synthase (nNOS). However, nNOS has not been identifie...
Effect of Chronic Ischemia on Constitutive and Inducible Nitric Oxide Synthase Expression in Erectile Tissue
Erectile dysfunction atherosclerosis blood flow oxygen tens
2008/12/22
Arterial occlusive disease is one of the leading causes of organic erectile dysfunction (ED). Recent studies have shown that the incidence of cardiovascular disease closely correlates with the preva...
Gingival Endothelial and Inducible Nitric Oxide Synthase Levels During Orthodontic Treatment: A Cross-Sectional Study
Orthodontic tooth movement Nitric oxide synthase Tissue remodeling/inflammation
2008/12/17
This study uses a cross-sectional design to examine the endothelial and inducible nitric oxide synthase (eNOS and iNOS, respectively) levels of gingival tissue. Fifteen subjects, 10 female and 5 mal...
Induction of inducible nitric oxide synthase mRNA expression and nitric oxide production from macrophages stimulated with high-molecular size mite antigen HM1
airway inflammation high-molecular size mite antigen HM1 inducible nitric oxide synthase nitric oxide
2006/2/3
Gene expression of TNF-α, IL-12 p40 and iNOS was observed with HM1 stimulation of splenic macrophages from non-immunized mice. In addition, the release of NO induced by HM1-stimulated splenic macropha...