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轻度认知功能障碍与neprilysin基因单核苷酸多态性的相关性
认知障碍 多态性 单核苷酸 脑啡肽酶基因
2010/3/28
分析轻度认知功能障碍(MCI)患者脑啡肽酶基因(NEP)rs3736187位点单核苷酸多态性,为MCI的防治提供理论依据。方法 参照美国精神病学会的精神障碍诊断和统计手册第4版(DSM-IV)的MCI诊断标准,应用聚合酶链反应-限制性片段长度多态性技术检测NEP基因多态性,采用病例-对照的关联分析方法,对NEP基因rs3736187位点进行基因型和等位基因频率分析。结果 NEP基因型频率和等...
The Comparison of the Podocyte Expression of Synaptopodin, CR1 and Neprilysin in Human Glomerulonephritis: Could the Expression of CR1 be Clinically Relevant?
glomerulonephritis podocytes CR1 neprilysin synaptopodin
2009/4/8
Podocytes are considered as the most important cells that determine loss of structure and function of the glomerular filter. We compared the expression of three podocyte markers, i.e.: synaptopodin (S...