搜索结果: 1-13 共查到“临床医学 leukotriene”相关记录13条 . 查询时间(0.046 秒)
Antitussive Effects of the Leukotriene Receptor Antagonist Montelukast in Patients with Cough Variant Asthma and Atopic Cough
atopic cough cough score cough variant asthma leukotriene receptor antagonist montelukast
2010/6/28
In patients with CVA, 2-week treatment with montelukast, clenbuterol, and montelukast plus clenbuterol all significantly decreased cough scores and treatment with montelukast plus clenbuterol was supe...
Molecular Mechanism of the Additive Effects of Leukotriene Modifier in Asthmatic Patients Receiving Steroid Therapy
airflow limitation airway hyperresponsiveness airway lability exhaled breath condensate RANTES
2009/3/11
A significant improvement in forced expiratory volume in one second as a percentage of the predicted value (%FEV1) and Min%Max PEF was seen in the subgroup of asthma with AR. Although there was no sig...
A Double-Blind Non-inferiority Clinical Study of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, Compared with Pranlukast in Patients with Seasonal Allergic Rhinitis
comparative double blind study cysteinyl leukotriene receptor montelukast pranlukast seasonal allergic rhinitis
2008/12/11
Montelukast 5mg, 10mg once daily and the pranlukast 450mg/day showed significant improvements in the change from the baseline in the composite, daytime and nighttime nasal symptom scores, and the impr...
The Role of Leukotriene B4 in Allergic Diseases
allergic conjunctivitis allergic rhinitis asthma atopic dermatitis
2008/12/11
Leukotriene B4 (LTB4) is a lipid mediator with potent chemoattractant properties and that is rapidly generated from activated innate immune cells such as neutrophils, macrophages, and mast cells. Elev...
Therapeutic Effect of Montelukast, a Cysteinyl Leukotriene Receptor 1 Antagonist, on Japanese Patients with Seasonal Allergic Rhinitis
cysteinyl leukotriene receptor dose-response relationship montelukast rhinitis allergic seasonal
2008/9/19
Background: Secretion of nasal discharge was enhanced and airway-resistance in the nasal cavity was augmented, resulting in nasal congestion, when leukotrienes were administered to the nasal mucosa. T...
Clinical Evaluation of Leukotriene Receptor Antagonists in Preventing Common Cold-like Symptoms in Bronchial Asthma Patients
acute exacerbation asthma common cold-like symptoms ICS LTRAs
2007/9/13
Adult asthma patients undergoing treatment with LTRAs exhibit lower incidence rates of common cold-like symptoms than those not receiving LTRAs. LTRAs play an important role in reducing the incidence ...
Population-based open-label clinical effectiveness assessment of the cysteinyl leukotriene receptor antagonist pranlukast
asthma pranlukast questionnaire symptom treatment
2006/3/16
Although the efficacy of cysteinyl leukotriene receptor antagonists in asthma therapy has been established through controlled clinical trials, there are no data concerning the effectiveness of their u...
Effect of a leukotriene receptor antagonist, pranlukast hydrate, on airway inflammation and airway hyperresponsiveness in patients with moderate to severe asthma
airway hyperresponsiveness airway inflammation asthma eosinophils leukotriene leukotriene receptor antagonist
2006/3/16
Asthma is characterized by chronic airway inflammation and the recruitment of inflammatory cells, typically eosinophils and lymphocytes, into the airway. Although several chemical mediators are releas...
Additive effect of cysteinyl leukotriene or thromboxane modifiers to inhaled corticosteroids in asthmatic patients
asthma corticosteroid cysteinyl leukotriene thromboxane
2006/1/19
Bronchial asthma is a chronic inflammatory disease of the conducting airways. Current asthma treatment guidelines recommend inhaled corticosteroids (ICS) as the first-line maintenance therapy for mild...
Urinary leukotriene E4 and 11-dehydro-thromboxane B2 excretion in children with bronchial asthma
bronchial asthma cysteinyl leukotrienes 11-dehydro-thromboxane B2 leukotriene E4 thromboxane A2
2006/1/19
Urinary LTE4 levels during an acute attack (median 476 pg/mg creatinine; range 191-1100 pg/mg creatinine) and during the stable condition (median 332 pg/mg creatinine; range 128-965 pg/mg creatinine) ...
Effect of a leukotriene receptor antagonist on the prevention of recurrent asthma attacks after an emergency room visit
β2-adrenergic receptor agonist asthma exacerbation leukotriene receptor antagonist montelukast
2006/1/19
In the montelukast group, the need for a rescue β-adrenergic receptor agonist was significantly decreased; 54.5% of patients in the montelukast group required use of β-adrenergic receptor agonist comp...
The Cysteinyl Leukotriene (CysLT) Pathway in Allergic Rhinitis
allergic rhinitis CysLT receptors CysLTs cytokines inflammation
2005/11/25
The cysteinyl leukotrienes (CysLTs), leukotriene C4(LTC4), leukotriene D4(LTD4 ) and leukotriene E4(LTE4 ) are released in response to specific allergen in nasal secretions from patients with active a...
Effect of a leukotriene receptor antagonist on cough receptor sensitivity and allergen-induced cough in a patient with atopic cough variant asthma
asthma atopy cough variant asthma leukotriene receptor antagonist
2005/10/14
A 24-year-old female patient with chronic dry cough, without wheezing and other symptoms, was diagnosed as atopic cough variant asthma (CVA) sensitized with house dust (HD) mite. To investigate the ef...