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Chemotherapy, estrogen, and cognition : neuroimaging and genetic variation
Chemotherapy estrogen cognition neuroimaging genetic variation
2015/5/21
The time course and biological mechanisms by which breast cancer (BC) and/or alterations in estrogen status lead to cognitive and brain changes remain unclear. The studies presented here use neuroimag...
Molecular Genetic Perspectives on the Origin of the Lyngngam Tribe of Meghalaya, India
Austro-Asiatics Admixture Autosomal STRs Y-Chromosome Markers MtDNA HVS-I and II Sequences
2012/11/22
Meghalaya, one of the Northeast Indian states, is inhabited by two major tribal clusters, Khasi and Garo. The disputed origin of the Lyngngam tribe of Meghalaya is a result of their geographic distrib...
A pseudorandom, velocity-insensitive, volumetric k-space sampling trajectory is designed for use with balanced steady-state magnetic resonance imaging. Individual arcs are designed independently and d...
Shape Optimization of THA Hip Stem using Genetic Algorithm
Total hip arthroplasty Optimization Genetic Algorithm
2009/6/1
Mechanical failure of the cemented hip stem is mainly caused by several cement mantle problems such as cement fracture. Geometries of the cement mantle and the stem are important factors of failure ri...
Genetic Studies of Bone Diseases: Evidence for Involvement of DNA Damage Response Proteins in Bone Remodeling
p53 Atm c-Abl osterix osteoblast osteoporosis
2009/4/20
Bone remodeling is carried out by bone marrow mesenchymal stem cell derived osteoblasts, which form the bones, and hematopoeitic stem cell derived osteoclasts, which absorb the bones. Their actions a...
Detection of Hemizygous Chromosomal Copy Number Variants in Williams-Beuren Syndrome (WBS) by Duplex Quantitative PCR Array: An Unusual Type of WBS Genetic Defect
human chromosome 7 deletion copy number variants genome
2009/4/14
We have developed a dual probe quantitative PCR (qPCR) mini array enabling a more accurate analysis of the relationship between copy number variants (CNVs) and other genomic features in specific areas...
Familial Genetic Analysis of Copper Transporting P-type ATPase（ATP7B）
Wilson's disease copper-transporting P-type ATPase (ATP7B) genetic analysis molecular diagnosis
2009/3/23
We have analyzed the copper-transporting P-type ATPase (ATP7B) gene responsible for Wilson's disease to provide an explanation for the early onset of acute hepatitis. The ATP7B coding sequence, includ...
Genetic Variation in ATP7B Promotor and 5' UTR in Han Chinese Patients with Wilson's Disease
Wilson's disease copper the ATP7B gene promoter metal response elements
2009/3/16
Wilson's disease (WD) is an autosomal recessive disorder of copper transport characterized by the accumulation of intracellular copper in the liver and extrahepatic tissues. The WD gene (ATP7B) encode...
Review of "Computational Modeling of Genetic and Biochemical Networks" edited by James M. Bower and Hamid Bolouri
Computational Modeling Genetic and Biochemical Networks James M. Bower Hamid Bolouri
2005/10/4
Since the coming-of-age of the scientific discipline called bioinformatics it has become increasingly clear that computers in biology will be important not only for managing and analyzing biological a...