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Reported evidence suggested that high abundance of intrinsic disorder in eukaryotic genomes in comparison to bacteria and archaea may reflect the greater need for disorder-associated signaling and tra...
The LysR Transcription Factor, HexS, Is Required for Glucose Inhibition of Prodigiosin Production by Serratia marcescens
Pigment Antibiotic Transcription Factor Secondary Metabolite
2012/12/27
Generation of many useful microbe-derived secondary metabolites, including the red pigment prodigiosin of the bacterium Serratia marcescens, is inhibited by glucose. In a previous report, a genetic ap...
Extraction of Transcription Factor Networks via Globally Optimal Biclustering
Bi-clustering Transcription Network Reconstruction
2009/12/24
We present an optimization-based framework for identifying and quantifying interactions transcription factor networks. We explore the availability of high-temporal resolution expression data using the...
A Common Polymorphism of Upstream Transcription Factor 1 Gene is associated with Lipid Profile: A Study in Chinese Type 2 Diabetes Families
dyslipidemia genetic epidemiology single nucleotide polymorphism type 2 diabetes mellitus upstream transcription factor
2009/10/30
Upstream transcription factor 1 (USF1) is capable of controlling various members in glucose and lipid metabolism pathways. Much evidence suggests that the rs3737787 polymorphism in the USF1 gene may l...
Metallothionein-IIA gene transcription in cisplatin-resistant cells and its metal-signalling mechanism by Cu(II) ion
Metallothionein-IIA gene transcription cisplatin-resistant cells metal-signalling mechanism
2009/4/1
Increased metallothionein (MT)-IIA transcription is found in some cells with acquired resistance to cisplatin (CDDP). It is also known that mammalian MT is induced by copper. MT induction by TPA (12-O...
Context specific Transcription Factor Prediction
Corticosteroids Gene expression Transcription factor binding site Phylogenetics
2007/3/22
Context specific Transcription Factor Prediction.