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近日，国际知名植物学期刊《New Phytologist》发表了刘天罡、鲁丽课题组在生物合成植物萜类天然产物方面的最新研究成果，标题为: “Complete pathway elucidation and heterologous reconstitution of (+)-nootkatone biosynthesis from Alpinia oxyphylla”。该研究利用萜类前体高效供应酵...
Huge libraries of drug compounds may hold potential treatments for a variety of diseases, such as cancer or heart disease. Ideally, scientists would like to experimentally test each of these compounds...
Researchers say we appear to be at the start of a new era for Alzheimer’s treatment. Trial results published in January showed that for the first time a drug has been able to slow the cognitive declin...
In the five years since the FDA’s initial approval of chimeric antigen receptor (CAR) T cell therapy, Penn Medicine has gleaned 20 additional approvals related to drugs and techniques to treat or dete...
MIT engineers have designed a two-component system that can be injected into the body and help form blood clots at the sites of internal injury. These materials, which mimic the way that the body natu...
A new control switch could make RNA therapies easier to program（图）
控制开关 RNA疗法 编程 治疗性RNA分子 癌细胞
2023/3/15
Using an RNA sensor, MIT engineers have designed a new way to trigger cells to turn on a synthetic gene. Their approach could make it possible to create targeted therapies for cancer and other disease...
In many instances, the physical manifestation of cancers and the ways they are subsequently diagnosed is via a tumor, tissue masses of mutated cells and structures that grow excessively. One of the ma...
Brown researchers develop new, automated, powerful diagnostic tool for drug detection（图）
药物检测 诊断工具 生物医学 抗抑郁药
2023/2/10
The work by a research team made up largely of Brown graduate and undergraduate students addresses a critical biomedical need and has the potential to be widely adapted by clinicians to monitor antide...
A new method could enable a patient’s own antibodies to eliminate their tumors（图）
肿瘤免疫学 抗体 靶向治疗
2022/6/2
One of the reasons that cancer is notoriously difficult to treat is that it can look very different for each patient. As a result, most targeted therapies only work for a fraction of cancer patients. ...
A serendipitous finding lends new insight into how atopic dermatitis develops（图）
特应性皮炎 皮肤病 皮肤
2022/2/11
Atopic dermatitis, a common skin condition affecting both children and adults, is often thought of as an inflammatory disease that arises from a breakdown in the barrier function of the skin. Now a ne...
Immunotherapy is a promising strategy to treat cancer by stimulating the body’s own immune system to destroy tumor cells, but it only works for a handful of cancers. MIT researchers have now discovere...
Over the past decade, scientists have been exploring vaccination as a way to help fight cancer. These experimental cancer vaccines are designed to stimulate the body’s own immune system to destroy a t...
郭睿教授团队在《New Journal of Chemistry》和《Journal of Inorganic Biochemistry》发表研究成果：功能化的Fe3O4纳米颗粒和氧化石墨烯作为纳米药物载体靶向递送抗癌药物并有效杀死肝癌细胞（图）
郭睿教授 山西医科大学 纳米药物 肝癌
2021/8/10
肝癌是世界范围内威胁人类健康的恶性肿瘤之一。临床上常见的治疗方式包括化疗与手术治疗等，然而化疗由于用药量大、药物靶向作用弱等缺点给患者带来了一系列严重副作用。因此，亟需设计并构筑一种具有良好的肝癌细胞靶向作用的多功能纳米药物载体，用于靶向递送抗癌药物并杀死肝癌细胞。
New technology paves way towards personalized antibiotic therapy New sensor provides quick test to measure antibiotic resistance
microwave sensor antibiotics resistance bacteria
2021/8/9
Researchers have developed a method for monitoring bacterial responses to antibiotics in health-care settings that opens the door to personalized antibiotic therapy for patients. Using microwave sensi...
New study offers insight on how resistance training burns fat
resistance movement reduced fat adipocyte metabolism
2021/8/9
Findings from a new study add to growing evidence that resistance exercise has unique benefits for fat loss. Researchers found that resistance-like exercise regulates fat cell metabolism at a molecula...