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Effect of Biochanin A on Serum Visfatin Level of Streptozocin-Induced Diabetic Rats
Visfatin Biochanin A Diabetic Rats
2014/10/14
Background: Bioflavonoids are well known for their multi directional biologic activity including antidiabetic effect. It has been demonstrated that flavonoids can act as insulin secretagogue or insuli...
检测2型糖尿病肾病患者血清visfatin、Apelin水平，探讨其在2型糖尿病肾病发生发展中的作用及临床意义。方法 根据24 h尿微量白蛋白排泄率(UAER)将105例2型糖尿病患者分为正常白蛋白尿组(NA组，39例)、微量白蛋白尿组(MA组，36例)、临床白蛋白尿组(CP组，30例)，选取健康者作为对照组(NC组，35例)。采用酶联免疫吸附法(ELISA)测定血清visfatin、Apelin...
Visfatin levels are low in subjects with type 2 diabetes compared to age-matched controls
Visfatin Adiponectin Resistin Diabetes Insulin Resistance
2012/11/22
Background: Visceral adiposity correlates strongly with insulin resistance and components of metabolic syndrome. Visfatin is preferentially produced by human visceral adipose tissue. Objective: The ob...
Variation in the visfatin gene may alter the required dosage of oral antidiabetic agents in type 2 diabetic patients
Visfatin Genotype Antidiabetic agents HOMA QUICKI Type 2 diabetes
2009/11/24
Background: Treatment of diabetes with oral antidiabetic agents is accompanied by considerable variability in pharmacokinetics and clinical efficacy. Genetic factors may contribute to individual diffe...
Cord Plasma Concentrations of Visfatin, Adiponectin and Insulin in Healthy Term Neonates: Positive Correlation with Birthweight
adiponectin visfatin insulin birthweight
2009/10/26
Objective: The aims of this study were to examine the relationships between adiponectin, insulin, visfatin and weight at birth in healthy term infants. Design and methods: Anthropometric parameters in...
Visfatin是新发现的由内脏脂肪细胞分泌的一种脂肪细胞因子，可结合并激活胰岛素受体的非胰岛素结合部位，激活胰岛素受体信号通路，从而模拟胰岛素作用，降低机体血糖。这一因子还能够促进脂肪组织的分化、合成及积累。Visfatin cDNA序列与前B细胞克隆增强因子（PBEF）相同，Visfatin在细胞内尚发挥尼克酰胺磷酸核糖转移酶(Nampt)的作用，通过调节氧化型辅酶I（NAD）的生成从而调控S...
Serum visfatin concentrations are positively correlated with serum triacylglycerols and down-regulated by overfeeding in healthy young men1,2,3
Visfatin insulin resistance lipids body composition nutritional regulation
2008/12/10
Background:Visfatin is an insulin-mimicking adipokine. Visfatin is elevated in obesity and type 2 diabetes. However, its role in glucose and lipid metabolism in healthy humans is unclear.Objective:The...