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骨质疏松症一种以骨量低下、骨组织微结构损坏,导致骨脆性增加,易发生骨折为特征的全身性骨病。大量研究证实,细胞外囊泡(EVs)在调控骨稳态的复杂机制中发挥重要的作用,这些囊泡在病理和生理环境中都起着至关重要的作用,而不同来源的EVs对骨质疏松症有明显且不同的影响。
2019年2月13日—17日,一年一度的北美颅底外科协会(NASBS)年会在美国召开,重医附一院神经外科杨刚主任医师作为中国参会的五名代表之一受邀出席并发表演讲,由他首创并命名的“In Situ Bone Flap”(原位骨瓣)在内镜下扩大经鼻入路术后颅底重建方面的经验轰动全场。
四川大学组织学与胚胎学英文课件 Bone and cartilage。
南昌大学组织学与胚胎学英文课件 Cartilage and bone。
Study:Changing the environment within bone marrow alters blood cell development
Changing the environment bone marrow blood cell development
2017/2/22
Researchers at the University of Illinois report they can alter blood cell development through the use of biomaterials designed to mimic characteristics of the bone marrow.The findings, reported in th...
Effects of an 8-Month Ashtanga-Based Yoga Intervention on Bone Metabolism in Middle-Aged Premenopausal Women: A Randomized Controlled Study
Yoga Sun Salutations bone formation bone resorption bone mineral density bone strength
2016/2/23
Although Yoga has the potential to be an alternative physical activity to enhance bone health, there is a lack of high quality evidence for this type of intervention. The purpose of this randomized co...
Effect of Nasal Calcitonin on the Health-Related Quality of Life in Postmenopause Women Affected With Low Bone Density
Osteoporosis Oteoporosis Postmenopausal Quality of Life Calcitonin Bone Density
2015/11/9
Background: Physical activity and mental health could be affected by osteoporosis and various therapeutic options such as calcitonin may influence Quality Of Life (QOL) of these patients with Low Bone...
Bone material properties and mineral matrix contributions to fracture risk or age in women and men
collagen osteoporosis
2014/12/4
The strength of bone is related to its mass and geometry, but also to the physical properties of the tissue itself. Bone tissue is composed primarily of collagen and mineral, each of which changes wit...
Introduction – Bone turnover and fracture risk
osteoporosis bone turnover fracture remodeling
2014/12/4
Introduction – Bone turnover and fracture risk.
Osteoporosis and fracture risk: bone matrix quality
remodeling bisphosphonates mineralization
2014/12/4
Osteoporosis and fracture risk: bone matrix quality.
Identification of material parameters based on Mohr-Coulomb failure criterion for bisphosphonate treated canine vertebral cancellous bone
material parameter identification Mohr-Coulomb failure criterion trabecular bone
2014/12/4
Nanoindentation has been widely used to study bone tissue mechanical properties. The common method and equations for analyzing nanoindentation, developed by Oliver and Pharr, are based on the assumpti...
Parathyroid Hormone Enhances Mechanically Induced Bone Formation, Possibly Involving L-Type Voltage- Sensitive Calcium Channels
parathyroid hormone bone formation
2014/12/4
PTH and mechanical loading might act synergistically on bone formation. We tested the in vivo effect of the L-type voltage-sensitive calcium channel (VSCC) blocker, verapamil, on bone formation induce...
Exercise-Induced Changes in the Cortical Bone of Growing Mice Are Bone and Gender Specific
mechanical properties pQCT matrix changes
2014/12/4
Fracture risk and mechanical competence of bone are functions of bone mass and tissue quality, which in turn are dependent on the bone's mechanical environment. Male mice have a greater response to no...
Effects of suppression of bone turnover on cortical and trabecular load sharing in the canine vertebral body
trabecular bone cortical shell suppressed bone turnover
2014/12/4
The relative biomechanical effects of antiresorptive treatment on cortical thickness vs. trabecular bone microarchitecture in the spine are not well understood. To address this, T-10 vertebral bodies ...
Alendronate treatment results in similar levels of trabecular bone remodeling in the femoral neck and vertebra
anti-remodeling bisphosphonates animal models
2014/12/4
Introduction Bone turnover suppression in sites that already have a low surface-based remodeling rate may lead to oversuppression that could have negative effects on the biomechanical properties of bo...