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Under normal conditions, smooth muscle cells do not replicate, or proliferate, and provide a means of contraction for many internal organs, including blood vessels and the gut. However, under abnormal...
Silent information regulator 1 (SIRT1) represents an NAD+-dependent deacetylase that inhibits proapoptotic factors including p53. Here we determined whether SIRT1 is downstream of the prototypic c-MYC...
To evaluate the effects of alendronate (ALN) and risedronate (RIS), which are agents for preventing and treating postmenopausal osteoporosis, on hepatic antioxidant enzyme activity and lipid peroxidat...
Background: Diabetes mellitus is a worldwide health problem affecting 1-2% of the population. It is responsible for numerous morbidity and mortality consequences due to vascular events such as hyperte...
Since most of the studies on chemical compounds of dermatophytes have shown the existence of a relationship between their pathogenisity and proteolytec enzymes. Activities of 19 different enzymes in v...
A pancreatopeptidase (Elastase) digest index was devised for a rapid and accurate estimation of protein quality. This index was calculated on the basis of all the amino acids released by an in-vitro E...
Aldehyde oxidase (EC 1.2.3.1), a cytosolic enzyme containing FAD, molybdenum and iron-sulphur cluster, is a member of non-cytochrome P-450 enzymes called molybdenum hydroxylases which is involved in t...
Opportunistic fungal infections including candidiasis have increased dramatically in recent years. Most medically important fungi are Candida species. Rapid identification od Candida isolates to the s...
Osteoporosis is a metabolic disease characterized by reduction in bone density and susceptibility to deformity and fracture. Some studies show that osteoblasts can create inter-cellular free radicals ...
Osteoporosis is a metabolic disease characterized by reduction in bone density and susceptibility to deformity and fracture. Some studies show that osteoblasts can create inter-cellular free radicals ...
To clarify the relationship between the alterations of the levels of angiotensin converting enzyme (ACE) and diabetic nephropathy, ACE activity in the lung, liver, kid-ney and serum were investigated ...
Malate Dehydrogenase (MDH) and Lactate Dehydrogenase (LDH) activities were demonstrated in the mitochondrial and cytosolic fractions of an intestinal cestode, Taenia saginata, and then the in vitro ef...
It is well recognized that diabetes mellitus is associated with an increase in kidney size, in both humans and experimental animals (1,2). The morphologic changes that occur in diabetic organs have be...
An important inorganic phase of synthetic bone applications, calcium hydroxyapatite (HA, Ca10 (PO 4 ) 6(OH2 ), was prepared as a single-phase and sub-micron bioceramic powder. Carbonated HA powders we...
Sulphydryl-containing captopril (CPR) appears to act as a scavanger of oxygen derived free radicals. This is not present in other angiotensin-converting enzymes such as enalapril (EPR). The hepatotoxi...

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