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Background: Diabetes mellitus is a worldwide health problem affecting 1-2% of the population. It is responsible for numerous morbidity and mortality consequences due to vascular events such as hyperte...
To clarify the relationship between the alterations of the levels of angiotensin converting enzyme (ACE) and diabetic nephropathy, ACE activity in the lung, liver, kid-ney and serum were investigated ...
It is well recognized that diabetes mellitus is associated with an increase in kidney size, in both humans and experimental animals (1,2). The morphologic changes that occur in diabetic organs have be...
Sulphydryl-containing captopril (CPR) appears to act as a scavanger of oxygen derived free radicals. This is not present in other angiotensin-converting enzymes such as enalapril (EPR). The hepatotoxi...

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