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Awarded Article, Annual Meeting of JSA Fibroblasts as Local Immune Modulators in Ocular Allergic Disease
conjunctiva cornea cytokine fibroblast vernal keratoconjunctivitis
2006/6/13
Vernal keratoconjunctivitis (VKC), a severe form of ocular allergic disease, is characterized by the formation of giant papillae at the upper tarsal conjunctiva and corneal lesions that threaten visio...
Cytokine and anti-cytokine therapy for the treatment of asthma and allergic disease
anti-interleukin-4 anti-interleukin-5 anti-tumor necrosis factor-α asthma cytokines
2006/1/19
Asthma is a chronic inflammatory disorder of the airways superimposed upon structural changes that include an increase in smooth muscle and airway wall remodeling. In addition to a background of chron...
Recent Developments in Genetic Study of Allergic Disease in the Japanese Population
allergic disease asthma atopy Japanese linkage polymorphism
2005/12/8
Allergy is a common immune disorder characterized by raised IgE levels, which leads to clinical disorders such as asthma, rhinitis and eczema. Our understanding of the pathogenesis of allergic disease...
IL-13/IL-13 Receptor Interaction, an Emerging Therapeutic Target in Allergic Disease
allergy antagonist asthma drug design interleukin-13 receptor
2005/11/25
Interleukin (IL)-13 is a Th-2 cytokine, known to be involved in allergic diseases. Although IL-13 and another Th-2 cytokine, IL-4, share receptors and signal pathways, having similar biological proper...