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Competition of the Histamine H2 Antagonist Cimetidine for Androgen Binding Sites in Man
cimetidine androgen binding prostate testis
2009/2/18
Gynecomastia and impotence have been described as side-effects of cimetidine therapy. It has previously been shown that cimetidine possesses antiandrogenic properties and competes for dihydrotesto...
Prolonged Histamine Deficiency in Histidine Decarboxylase Gene Knockout Mice Affects Leydig Cell Function
Steroidogenesis human choriogonadotropin
2008/12/24
The present study focuses on histaminergic regulation of Leydig cell physiology, since limited information is available so far. To evaluate the dependency of Leydig cells on histamine (HA), we pe...