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Development of transmembrane signaling in the fetal rat Leydig cell
transmembrane signaling fetal rat Leydig cell
2009/2/23
Gonadotropin binding to the adult Leydig cell activates a GTP binding protein that interacts with adenylate cyclase to increase cAMP production within the cell. The increased production of cAMP stim...
Adhesion and signaling proteins spatiotemporally associated with spermiation in the rat
Adhesion signaling proteins spermiation rat
2009/2/18
Spermiation, the process by which late spermatids separate from the Sertoli cell, is disrupted by a number of toxicants. In this study, we used immunohistochemistry (IHC) to identify some of the p...
Actin and actin-binding proteins in bovine spermatozoa：potential role in membrane remodeling and intracellular signaling during epididymal maturation and the acrosome reaction
proteins bovine spermatozoa potential role signaling epididymal maturation
2008/12/26
The actin cytoskeleton influences a wide range of functions in nonmuscle somatic cells, including shape, movement, and interactions with extracellular matrices. The role of actin in mammalian male ger...
SAMMA Induces Premature Human Acrosomal Loss by Ca2+ Signaling Dysregulation
Topical contraceptive microbicide signal transduction spermatozoa mechanism calcium channels
2008/12/24
SAMMA is licensed for development as a contraceptive microbicide. Understanding mechanisms of its biological activity is prerequisite to designing more active second generation products. This study ...
The Multi PDZ Domain Protein MUPP1 as a Putative Scaffolding Protein for Organizing Signaling Complexes in the Acrosome of Mammalian Spermatozoa
Signal transduction acrosome reaction MPDZ
2008/12/24
Spermatozoa undergo complex sequences of precisely timed events during the process of fertilization. These priming events, which comprise capacitation, egg recognition, acrosome reaction, and sperm-...
A Cyclic Adenosine 3',5'-Monophosphate Stimulates Phospholipase C1-Calcium Signaling via the Activation of Tyrosine Kinase in Boar Spermatozoa
Sperm cAMP SYK PLC calcium store
2008/12/23
The aim of this study was to reveal a downstream part of the intracellular signaling that is mediated by cyclic adenosine monophosphate (cAMP)-dependent tyrosine kinases, including spleen tyrosine (...
Synopsis：XVIIIth Testis Workshop,“Testicular Cell Dynamics and Endocrine Signaling”
XVIIIth Testis Workshop Testicular Cell Dynamics Endocrine Signaling
2008/12/23
The Testis Workshop convened in Seattle, Wash, from March 30 to April 2 at the Grand Hyatt Hotel. The theme for 2005 was "Testicular Cell Dynamics and Endocrine Signaling." Recent years have brought a...
Impaired Sperm Function After Spinal Cord Injury in the Rat Is Associated With Altered Cyclic Adenosine Monophosphate Signaling
cAMP SYBR-14 JC-1
2008/12/23
Our previous observations of changes in the expression of cAMP-dependent genes and the cAMP-responsive element modulator (CREM) in rat testicular cells after spinal cord injury (SCI) implied abnor...
Expression of the p63 and Notch Signaling Systems in Rat Testes During Postnatal Development：Comparison With Their Expression Levels in the Epididymis and Vas Deferens
Spermatogenesis p53 differentiation
2008/12/22
The role of tubular structures that contribute to the passage of spermatozoa is not solely passive; these structures actively contribute to their own functions, although these tubules and ducts ar...
Estrogenic Regulation of Signaling Pathways and Homeobox Genes During Rat Prostate Development
Estrogenic Regulation Signaling Pathways Homeobox Genes Rat Prostate Development
2008/12/22
The developing prostate gland is regulated by its hormonal milieu, most notably androgens, which dictate its growth and differentiation (Price, 1936; Lasnitzki and Mizuno, 1980). In addition, the ...