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Coffee bean extracts rich and poor in kahweol both give rise to elevation of liver enzymes in healthy volunteers
kahweol Coffee
2008/4/23
Coffee oil potently raises serum cholesterol levels in humans. The diterpenes cafestol and kahweol are responsible for this elevation. Coffee oil also causes elevation of liver enzyme levels in serum....
Skeletal muscle enzymes as predictors of 24-h energy metabolism in reduced-obese persons
Obesity weight loss energy expenditure
2003/1/4
This study was performed retrospectively to investigate the relation between skeletal muscle enzymes and 24-h energy metabolism in obese persons before and after weight loss.
High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased Km):relevance to genetic disease and polymorphisms
Genetic disease therapeutic vitamin use binding defect favism alcohol intolerance autism migraine headaches single nucleotide polymorphisms enzyme mutations review
2002/3/17
As many as one-third of mutations in a gene result in the corresponding enzyme having an increased Michaelis constant, or Km, (decreased binding affinity) for a coenzyme, resulting in a lower rate of ...