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Genetic, dietary, and other lifestyle determinants of plasma homocysteine concentrations in middle-aged and older Chinese men and women in Singapore
Homocysteine folate vitamin B-12
2016/6/12
Epidemiologic studies have identified the plasma
homocysteine concentration as a risk factor for atherothrombotic
vascular disease. There is little information on the distributions and
determinants...
Genetic and environmental influences on eating patterns of twins aged ≥50 y
eating patterns genetic influences eating behavior
2016/6/1
Clinicians and researchers could benefit from a
greater understanding of the role of genetic and environmental
factors in human eating behavior.
Genetic effects on weight change and food intake in Swedish adult twins
weight gain Swedish Twin Registry monozygotic twins,
2016/5/30
Obesity is influenced by genetic and environmental
factors. Additionally, synergistic effects of genes and environments
may be important in the development of obesity
The relation of magnesium and calcium intakes and a genetic polymorphism in the magnesium transporter to colorectal neoplasia risk 1,2,3
Magnesium calcium ratio of magnesium to calcium intake
2009/4/20
Background: Mean magnesium intake in the US population does not differ from that in East Asian populations with traditionally low risks of colorectal cancer and other chronic diseases, but the ratio...
Same genetic components underlie different measures of sweet taste preference
Twin study sweet taste genetic effects heritability taste preferences
2008/12/17
Background: Sweet taste preferences are measured by several often correlated measures.Objective: We examined the relative proportions of genetic and environmental effects on sweet taste preference ind...
Genetic variation and the lipid response to dietary intervention: a systematic review
Genetic variation lipid response
2003/12/30
There is wide interindividual variation in the lipid and lipoprotein responses to dietary change, and the existence of consistent hypo- and hyperresponders supports the hypothesis that responsiveness ...
Genetic variants of Clock transcription factor are associated with individual susceptibility to obesity
Genetic variants susceptibility
2003/12/30
Lean (n = 715) and overweight or obese (n = 391) unrelated subjects aged 34.4 ± 8.6 y were included in a population-based cross-sectional study. Six tag single-nucleotide polymorphisms (SNPs) with a m...
High-dose vitamin therapy stimulates variant enzymes with decreased coenzyme binding affinity (increased Km):relevance to genetic disease and polymorphisms
Genetic disease therapeutic vitamin use binding defect favism alcohol intolerance autism migraine headaches single nucleotide polymorphisms enzyme mutations review
2002/3/17
As many as one-third of mutations in a gene result in the corresponding enzyme having an increased Michaelis constant, or Km, (decreased binding affinity) for a coenzyme, resulting in a lower rate of ...
Genetic underpinnings of LDL size and density: a role for hepatic lipase?1
LDL size epatic lipase
2000/6/7
Plasma lipoprotein abnormalities underlie and may even be
essential for the common occurrence of atherosclerotic vascular
diseases in Western societies. The abnormalities include elevated
concentra...
Given the major impact of nutrients such as saturated fat and
cholesterol on plasma lipoproteins, it is reasonable to suppose that
interindividual variations in genes affecting lipoprotein metabolis...
Apolipoprotein B gene polymorphisms and serum lipids: meta-analysis of the role of genetic variation in responsiveness to diet
Apolipoprotein B cholesterol diet meta-analysis, human polymorphism restriction endonuclease restrictionfragment-length polymorphism restriction-site polymorphism, plasma lipids
2000/3/3
Background: The genetic variance determining plasma lipid and
lipoprotein concentrations may modify individual responsiveness
to alterations in dietary fat and cholesterol content.
Objective: The a...