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A protein domain once considered of little importance may be key to helping patients who are fighting acute myeloid leukemia (AML) avoid a relapse.Researchers at Rice University, working wit...
Successful Treatment of Life-Threatening Cerebral Bleeding Associated with Disseminated Intravascular Coagulation Using Recombinant Human Soluble Thrombomodulin in a Patient with Mixed Phenotype Acute Leukemia with t (9; 22) (q34; q11.2); Bcr-Abl1
Mixed Phenotype Acute Leukemia with t (9 22) (q34 q11.2) Bcr-Abl1
2013/1/29
Recently, mixed phenotype acute leukemia (MPAL) with t (9; 22) (q34; q11.2); bcr-abl1 was described as one kind of acute leukemia of ambiguous lineage in the 2008 World Health Organization Classificat...
Obesity and childhood survivors of acute lymphoblastic leukemia: Do genetics play a role?
Genetic Polymorphisms Obesity Metabolic Syndrome Acute Lymphoblastic Leukemia
2012/12/31
Childhood survivors of acute lymphoblastic leukemia (ALL) are increased risk of several chronic complications, such as second cancers, pulmonary, metabolic complications and cardiovascular disease. Ob...
Gossypol-induced Differentiation in Human Leukemia HL-60 Cells
gossypol differentiation leukemia drug effects
2009/4/20
The main treatment of leukemia is traditional radiochemotherapy, which is associated with serious side effects. In the past twenty years, differentiation was found as an important effective measure to...
Effects of tea constituents on cell cycle progression of human leukemia U937 cells
tea constituents cell cycle progression human leukemia U937 cells
2009/3/2
Tea and tea constituents are known to induce apoptosis in a variety of cancerous cells, suggesting their beneficial effects as chemopreventive agents. Previous studies have shown that low molecular ...
DNA microarray analysis of changes in gene expression induced by 1,25-dihydroxyvitamin D3 in human promyelocytic leukemia HL-60 cells
DNA microarray analysis gene expression 1,25-dihydroxyvitamin D3 promyelocytic leukemia HL-60 cells
2009/3/2
Using a DNA microarray, we analyzed about 16,600 genes for changes in expression associated with the differentiation of human promyelocytic leukemia HL-60 cells induced by 1α,25-dihydroxyvitamin D3 ...
1,25-Dihydroxyvitamin D3 suppresses exportin expression in human promyelocytic leukemia HL-60 cells
1,25-Dihydroxyvitamin D3 human promyelocytic leukemia HL-60 cells
2009/3/2
The active form of vitamin D3, 1α,25-dihydroxyvitamin D3 (DVD), is a potent inducer of cell differentiation and inhibits proliferation of cells such as human promyelocytic leukemia HL-60 cells. In t...
Differentiation-associated alteration in gene expression of importins and exportins in human leukemia HL-60 cells
gene expression human leukemia HL-60 cells
2009/3/2
Employing the DNA microarray technique, we previously reported the alteration in gene expression of nucleocytoplasmic transport factors, importins and exportins, induced by 1,25-dihydroxyvitamin D3 ...